| 发明名称 |
CLONED PORPHYROMONAS GINGIVALIS GENES AND PROBES FOR THE DETECTION OF PERIODONTAL DISEASE |
| 摘要 |
DNA fragments from Porphyromonas gingivalis which express hemagglutinin/proteases that elicit anti-P. gingivalis immunologic responses are described. Microorganisms, genetically modified to express P. gingivalis antigens, are provided. Also disclosed are probes, vaccines, and monoclonal antibodies for the detection and prevention of periodontal disease.
|
| 申请公布号 |
CA2206664(A1) |
申请公布日期 |
1996.06.13 |
| 申请号 |
CA19952206664 |
申请日期 |
1995.12.11 |
| 申请人 |
LEPINE, GUYLAINE;UAB RESEARCH FOUNDATION;UNIVERSITY OF FLORIDA |
发明人 |
LEPINE, GUYLAINE;PATTI, JOSEPH M.;HAN, NAIMING;LANTZ, MARILYN;PROGULSKE-FOX, ANN;TUMWASORN, SOMYING |
| 分类号 |
C12N15/02;A61K31/00;A61K38/00;A61K39/00;A61K39/02;A61P1/00;A61P1/02;C07K14/195;C07K16/12;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/52;C12N15/09;C12N15/31;C12P21/08;C12Q1/68;G01N33/569;(IPC1-7):C12N15/31;A61K48/00;C12N15/57;A61K31/70 |
主分类号 |
C12N15/02 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
