ENHANCED IMMUNE RESPONSE BY INTRODUCTION OF CYTOKINE GENE AND/OR COSTIMULATORY MOLECULE B7 GENE IN A RECOMBINANT VIRUS EXPRESSING SYSTEM
摘要
The present invention is a recombinant virus which has incorporated into its genome or portion thereof a gene encoding an antigen at a disease causing agent in combination with an immunostimulatory molecule for the purpose of stimulating an immune response against the disease causing agent. Methods of treatment of diseases such as cancer and diseases caused by pathogenic microorganisms are provided using the recombinant virus.
申请公布号
WO9611279(A2)
申请公布日期
1996.04.18
申请号
WO1995US12638
申请日期
1995.10.02
申请人
THE GOVERNMENT OF THE UNITED STATES OF AMERICA, RE
发明人
ROSENBERG, STEVEN, A.;RESTIFO, NICHOLAS, P.;MOSS, BERNARD