发明名称 |
Method of immunological assaying of human osteocalcin, reagent and kit therefor, antibody to human osteocalcin, hybridoma producing said antibody, and method of producing it |
摘要 |
A method of immunologically assaying intact human osteocalcin in a human assay sample is provided by using an antibody having an epitope in a region of an amino acid sequence 1 to 20 on the N-terminal side of human osteocalcin and an antibody having an epitope in a region of an amino acid sequence 36 to 49 on the C-terminal side of human osteocalcin. A reagent and a kit therefor are provided. Furthermore, a method of immunologically assaying the total amount of human intact osteocalcin in a human assay sample, and a reagent and a kit therefor are also provided. A monoclonal antibody and a polyclonal antibody are used for the assay. A process for producing these antibodies, and utilization of these antibodies is described.
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申请公布号 |
US5506111(A) |
申请公布日期 |
1996.04.09 |
申请号 |
US19940316364 |
申请日期 |
1994.10.03 |
申请人 |
TEIJIN LIMITED |
发明人 |
HOSODA, KENJI;HONDA, HITOMI;KUBOTA, TAKAHARU;MASUHO, YASUHIKO |
分类号 |
C07K14/78;C07K16/18;G01N33/68;(IPC1-7):G01N33/53 |
主分类号 |
C07K14/78 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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