| 摘要 |
PCT No. PCT/SE94/01095 Sec. 371 Date Jul. 22, 1996 Sec. 102(e) Date Jul. 22, 1996 PCT Filed Nov. 18, 1994 PCT Pub. No. WO95/14477 PCT Pub. Date Jun. 1, 1995The present invention relates to the use of an ester of inositoltrisphosphate for the preparation of a medicament for preventing, alleviating or combatting inflammatory conditions in mammals including man. Injury or destruction of tissues should be understood as damage to an aggregation of specialized cells with a particular function both internally and externally in the body, such as different organs or parts of these, vessels, skin etc. Tissue damage involves a complex series of events such as dilatation of vessel walls e.g. arterioles, capillaries and venules, increased permeability of fluids including e.g. plasma proteins and increased blood flow. Increased vascular leakage often results in extravasation and oedema formation which characterize the damage of different tissues. Often tissue damage and inflammatory conditions are characterized by signs of pain, heat, redness, swelling and loss of function. Tissue damage is not defined as a disease per se but is often a component in different diseases of both acute or chronic nature. |
