| 发明名称 |
SUBSTITUTED AZETIDINONES AS ANTI-INFLAMMATORY ANTIDEGENERATIVE AGENTS |
| 摘要 |
New substituted azetidinones of Formula I are found as potent elastase inhibitors and thereby useful antiinflammatory and anti-degenerative agents <IMG> (I) The active substituted azetidinones can be used to provide pharmaceutical compositions as protease inhibitors useful for controlling tissue damage and various inflammatory or degenerative conditions mediated by proteases particularly elastase.
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| 申请公布号 |
CA1337990(C) |
申请公布日期 |
1996.01.23 |
| 申请号 |
CA19890595997 |
申请日期 |
1989.04.07 |
| 申请人 |
MERCK & CO., INC. |
发明人 |
SHAH, SHRENIK K.;FINKE, PAUL E.;DOHERTY, JAMES B.;BARKER, PETER L.;HAGMANN, WILLIAM;DORN, CONRAD P.;FIRESTONE, RAYMOND A. |
| 分类号 |
A61K31/395;A61K31/397;A61K31/41;A61K31/415;A61K31/44;A61K31/4427;A61K31/443;A61K31/4433;A61P29/00;A61P43/00;C07D205/08;C07D401/04;C07D401/06;C07D401/08;C07D401/12;C07D403/00;C07D403/04;C07D403/12;C07D405/00;C07D405/12;C07D409/12;C07D521/00;(IPC1-7):C07D205/08 |
主分类号 |
A61K31/395 |
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