| 摘要 |
<p>Diphosphate or triphosphate non-hydrolysable stable analogues and methods for their preparation. These analogues are of formula (I) in which R?1, R2, R3, R4 and R5¿ are a hydrocarbon group, an aryl group, a quaternary ammonium group or a metal ion, R5 can also be a nucleoside derivative, X?1 and X2¿ are CH¿2?, CHF, CF2, CC12, CHC1 or NR?6¿ and n=0 or 1. The analogues of the invention are for pharmaceutical, biological and therapeutical use.</p> |
