| 发明名称 |
Modified guanidino and amidino thrombin inhibitors |
| 摘要 |
<p>Thrombin inhibitors are provided which have the formula <CHEM> wherein Z is a thrombin inhibitor substructure containing distal and proximal binding site residues; and R<1> is cyano, hydroxyl, alkoxy, amino, aminoalkyl or nitro.wher</p> |
| 申请公布号 |
EP0686642(A2) |
申请公布日期 |
1995.12.13 |
| 申请号 |
EP19950108266 |
申请日期 |
1995.05.30 |
| 申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
KIM, KYOUNG S.;KIMBALL, SPENCER D.;DAS, JAGABANDHU;IWANOWICZ, EDWIN J.;HAN, WEN-CHING |
| 分类号 |
C07D211/20;A61K31/155;A61K31/275;A61K31/40;A61K31/4427;A61K31/445;A61K31/451;A61K38/00;A61P29/00;A61P7/02;A61P9/00;A61P9/08;A61P9/10;A61P31/04;A61P35/00;A61P43/00;C07D207/09;C07D207/12;C07D207/16;C07D211/32;C07D211/56;C07D211/58;C07D211/60;C07D401/12;C07D401/14;C07D413/12;C07D413/14;C07K5/02;C07K5/06;C07K5/062;C07K5/065;C07K5/068;C07K5/072;C07K5/078;C07K5/083;(IPC1-7):C07K5/06;C07K5/08;A61K31/395;C07D207/04;C07D211/06;A61K38/55 |
主分类号 |
C07D211/20 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
