METHODS OF DIAGNOSING ULCERATIVE COLITIS AND CROHN'S DISEASE

摘要

A novel association between inflamatory bowel disease (IBD) and a polymorphism at amino acid residue 241 or intracellular adhesion molecule-1 ICAM-1 has been discovered. In accordance with the present invention there is provided methods of screening for IBD, methods for treating IBD, antibodies specifically reactive with ICAM-1 encoded by R241 allele and kits which exploit the inventive methods.