发明名称 Phenylnaphthalene hydroxy acids
摘要 Compounds having the formula I: <IMAGE> I are inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis, and allograft rejection and in preventing the formation of atherosclerotic plaques.
申请公布号 US5426109(A) 申请公布日期 1995.06.20
申请号 US19920936811 申请日期 1992.08.27
申请人 MERCK FROSST CANADA, INC. 发明人 GIRARD, YVES;HAMEL, PIERRE
分类号 A61K45/06;C07D405/04;C07D493/08;(IPC1-7):A61K31/19;A61K31/33;A61K31/335;A61K31/38;A61K31/395;A61K31/44 主分类号 A61K45/06
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