Process for preparing epibatidine.

摘要

The subject-matter of the invention is a process for preparing racemic or optically active epibatidine of formula which comprises subjecting racemic or optically active epi-epibatidine of formula to epimerization in the presence of a base or cyclising a 1-[diacylamino]-2-[6'-chloro)-pyrid-3'-yl]-4-[amino]-cyclohexane of general formula wherein Ac stands for an acyl group. The advantage of the process is that readily available starting materials are used and the procedure is suitable for industrial scale productions, too.