BENZANILIDE DERIVATIVES AS 5HT-1D RECEPTOR ANTAGONISTS

摘要

Amide derivatives of formula (I) or a salt thereof, in which R<1> is halogen, C3-6cycloalkyl, optionally substituted phenyl or an optionally substituted 5-7-membered heterocyclic ring containing 1 to 3 heteroatoms selected from oxygen, nitrogen or sulphur; R<2> is hydrogen, halogen, C1-6alkyl, C1-6alkoxy, acyl, nitro, trifluoromethyl or cyano; R<3> is hydrogen or C1-6alkyl; and A is -(CR<4>R<5>)m- or -O(CR<4>R<5>)n- where R<4> and R<5> are independently hydrogen or C1-6alkyl, m is 2, or 3; n is 1, 2 or 3 and B is CONH or NHCO, processes for their preparation, and pharmaceutical compositions containing them.