| 摘要 |
The present invention is directed to diagnostic reagents for the detection of antibodies against the Epstein Barr Virus and a method for the detection of antibodies to the Epstein Barr Virus in a sample. The diagnostic reagents according to the invention comprise a combination of at least part of an Epstein Barr viral structural protein, preferably a Epstein Barr VCA-protein or an Epstein Barr MA protein, and at least part of an Epstein Barr EBNA protein. Preferably, the VCAprotein is VCA-p18 protein, the MA-protein is MAgp350/220 protein and the EBNA-protein is EBNA-1 protein. It has been found that the combination of a VCA-protein or a MA protein, and an EBNA protein, into a single diagnostic assay yields an EBVantibody detection method with greater sensitivity and accuracy than current methods.
|
