1,4-dihydro-4-oxo-3-quinoline derivatives as selectively toxic mammalian antibacterial agents

摘要

PCT No. PCT/US89/04438 Sec. 371 Date Mar. 26, 1992 Sec. 102(e) Date Mar. 26, 1992 PCT Filed Oct. 6, 1989 PCT Pub. No. WO91/04972 PCT Pub. Date Apr. 18, 1991.Compounds of the formula <IMAGE> and the pharmaceutically acceptable salts thereof, wherein Q, X and R are as defined below. The compounds of formula I are broad spectrum mammalian antibacterial agents and exhibit favorable selectivity against procaryotic cells.