| 摘要 |
PCT No. PCT/US96/08528 Sec. 371 Date Dec. 11, 1997 Sec. 102(e) Date Dec. 11, 1997 PCT Filed Jun. 4, 1996 PCT Pub. No. WO97/00252 PCT Pub. Date Jan. 3, 1997Compounds of formula I wherein X is N or C-R9, Y is N-R10, CH2, O, S, SO, SO2, C=O or CH-OH, R is H or alkyl, R1 is heteroaryl, n is 1-5, and R2-R10 are H or various substituents, are useful as inhibitors of protein farnesyl transferase and for the treatment of proliferative diseases including cancer, restenosis and psoriasis, and as antiviral agents. |
