| 发明名称 |
BIFUNCTIONAL VARIANTS OF UROKINASE WITH IMPROVED FIBRINOLYTIC PROPERTIES AND THROMBIN-INHIBITING ACTIVITY |
| 摘要 |
Bifunctional urokinase variants possessing improved fibrinolytic properties and thrombin inhibitory activities, plasmids used in the production of these polypeptides, as well as thrombolytic agents containing one of the bifunctional urokinase variants as active ingredient are described.
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| 申请公布号 |
CA2127897(A1) |
申请公布日期 |
1995.01.16 |
| 申请号 |
CA19942127897 |
申请日期 |
1994.07.13 |
| 申请人 |
GRUENENTHAL GMBH |
发明人 |
STEFFENS, GERD J.;WNENDT, STEPHAN;SCHNEIDER, JOHANNES;HEINZEL-WIELAND, REGINA;SAUNDERS, DEREK J. |
| 分类号 |
C12N15/09;A61K38/00;A61K38/46;A61K38/49;A61K38/55;A61P7/02;C07K14/81;C07K19/00;C12N9/72;C12N15/58;C12N15/62;C12R1/19;(IPC1-7):C12N9/72;C12N15/70 |
主分类号 |
C12N15/09 |
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