| 发明名称 |
Cd40-interacting and traf-interacting proteins |
| 摘要 |
The present invention relates to novel proteins interacting with the cytoplasmic domain of CD40, which are useful in the treatment of CD40 and/or NF-kB related diseases. Surprisingly, these proteins do not show significant homology with the TRAF-protein family and therefore offer the possibility to modulate the CD40 and/or NF-kB pathway independently from the TRAF-CD40 interaction. |
| 申请公布号 |
AU3931099(A) |
申请公布日期 |
1999.11.16 |
| 申请号 |
AU19990039310 |
申请日期 |
1999.04.28 |
| 申请人 |
VLAAMS INTERUNIVERSITAIR INSTITUUT VOOR BIOTECHNOLOGIE VZW |
发明人 |
STEFAN MARIA CHRISTIAAN PYPE;JACQUES EMILE FERNAND JOSIANE GHISLAI REMACLE;DANNY FRANCOIS EVELINE HUYLEBROECK |
| 分类号 |
G01N33/50;A61K38/00;A61K38/17;A61P9/10;A61P19/02;A61P25/00;A61P35/00;A61P37/02;A61P37/06;A61P43/00;C07K14/47;C07K16/18;C12N15/09;C12N15/12;C12Q1/68;G01N33/15;G01N33/566 |
主分类号 |
G01N33/50 |
| 代理机构 |
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