发明名称 Composition and method of treating hearing loss
摘要 A composition for treating hearing loss includes components that function through different biological mechanisms to provide an additive effect that is greater than the effect of the individual components alone. The composition includes a biologically effective amount of vitamin E for inhibiting propagation of lipid peroxidation that contributes to hearing loss. The composition also includes a biologically effective amount of a salicylate for reducing hydroxyl radicals that contribute to hearing loss. A method of treating hearing loss includes the step of internally administering the composition, as described above, to a mammal within three days of trauma to a middle or inner ear of the mammal. In other words, the composition is effective even when administered as late as three days after trauma to a middle or inner ear of a mammal.
申请公布号 US2007219167(A1) 申请公布日期 2007.09.20
申请号 US20060384579 申请日期 2006.03.20
申请人 THE REGENTS OF THE UNIVERSITY OF MICHIGAN 发明人 MILLER JOSEF;GARBE-LEPRELL COLLEEN;YAMASHITA DAISUKE
分类号 A61K31/355;A61K31/60 主分类号 A61K31/355
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