| 摘要 |
PCT No. PCT/FR92/00057 Sec. 371 Date Nov. 17, 1992 Sec. 102(e) Date Nov. 17, 1992 PCT Filed Jan. 22, 1992 PCT Pub. No. WO92/12978 PCT Pub. Date Aug. 6, 1992.The invention relates to ligands of formularoup, in which groups X and Z represent a heterocycle. The invention also relates to the monometallic or polymetallic complexes formed by these ligands with metal ions chosen from lanthanide ions, transition metal ions. barium, bismuth, lead and the radioisotopes 99mTc, 111In, 90Y, 64Cu and 169Yb, as well as the physiologically acceptable salts of these complexes. The salts of these complexes may be used as diagnostic or therapeutic agents in nuclear magnetic resonance imaging and X-ray radiology, as in-vivo chemical shift agents and in nuclear medicine. No figure
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