摘要 |
A polypeptide exhibiting the antigenicity of Mycoplasma gallisepticum, a fused polypeptide comprising the above polypeptide and, connected to the N-terminus thereof, a signal membrane anchor of a type II outer-membrane polypeptide of a virus that infects birds, or a polypeptide capable of reacting with a mycoplasma-immune serum or a mycoplasma-infected serum and exhibiting a substantially pure antigenicity, respectively having amino acid sequences of about 32 kDa, about 40 kDa, or about 70kDa. The expression w ith a recombinant virus of a polypeptide modified to such an extent as to exhibit an antigenicity equivalent to that of any of the above polypeptides. The use of a recombinant virus as a live vaccine. |
申请人 |
NIPPON ZEON CO., LTD.;SHIONOGI & CO., LTD.;SAITO, SHUJI;OHKAWA, SETSUKO;SAEKI, SAKIKO;OHSAWA, IKUROH;FUNATO, HIRONO;IRITANI, YOSHIKAZU;AOYAMA, SHIGEMI;TAKAHASHI, KIYOHITO |
发明人 |
SAITO, SHUJI;OHKAWA, SETSUKO;SAEKI, SAKIKO;OHSAWA, IKUROH;FUNATO, HIRONO;IRITANI, YOSHIKAZU;AOYAMA, SHIGEMI;TAKAHASHI, KIYOHITO |