发明名称 Process for preparing ethyl ester of L-DOPA
摘要 A composition which comprises a pharmaceutically acceptable carrier and an active ingredient, such active ingredient comprising L-DOPA ethyl ester in an amount which is at least 97%, by weight, of the active ingredient, and L-DOPA in an amount which is less than 1% by weight of such active ingredient is provided by this invention. This invention also provides a process for preparing such a composition. Further, this invention provides a method of treating a patient suffering from Parkinson's disease which comprises administering to a patient a pharmaceutical composition comprising a therapeutically effective amount of L-DOPA ethyl ester and a pharmaceutically acceptable carrier.
申请公布号 US5354885(A) 申请公布日期 1994.10.11
申请号 US19920995847 申请日期 1992.12.24
申请人 YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM;TEVA PHARMACEUTICAL INDUSTRIES LTD. 发明人 MILMAN, ISAAC;VEINBERG, ALEXANDER;ATLAS, DAPHNE;MELAMED, ELDAD
分类号 A61K9/08;A61K31/195;A61K31/215;A61K31/216;A61K47/02;A61K47/12;A61P25/00;A61P25/16;C07C229/36;(IPC1-7):C07C229/00;A61K31/135 主分类号 A61K9/08
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