发明名称 Certain substituted phenoxy-methyl phenyl-methoxy benzenes having antiviral activity
摘要 A compound represented by formula I Ar1-O-M-O-Ar2 I wherein Ar1 and Ar2 are independently substituted phenyl or substituted pyridinyl, the substituents on said phenyl or pyridinyl being independently selected from one, two or three of (C1-C10) alkyl, (C1-C10) alkoxy, halogen, carbamyl, (C1-C10) alkoxycarbonyl, oxazoyl, and (C1-C10) alkyl substituted by halogen, (C1-C10) alkoxy, hydroxy, or (C1-C10) alkoxycarbonyl; M is <IMAGE> (C4-C8) alkylene, (C4-C8) alkenylene or (C4-C8)-alkynylene; O is oxygen; or pharmaceutically acceptable salts thereof. as well as pharmaceutical compositions containing the compounds and methods of treating or preventing viral infections, especially picornaviral infections, are disclosed.
申请公布号 US5350772(A) 申请公布日期 1994.09.27
申请号 US19930039532 申请日期 1993.03.26
申请人 SCHERING CORPORATION 发明人 GIRIJAVALLABHAN, VIYYOOR M.;GANGULY, ASHIT K.;VERSACE, RICHARD W.
分类号 A61K31/085;A61K31/09;A61K31/185;A61K31/235;A61K31/34;A61K31/341;A61K31/38;A61K31/381;A61K31/42;A61K31/421;A61P31/00;C07C43/205;C07C43/225;C07C43/23;C07C69/92;C07C205/38;C07C233/25;C07C255/54;C07C317/22;C07C323/19;C07D213/30;C07D213/65;C07D263/12;C07D263/14;C07D307/12;C07D307/28;C07D307/42;C07D333/16;(IPC1-7):A61K31/09;C07C43/220 主分类号 A61K31/085
代理机构 代理人
主权项
地址