NOVEL ARYLOXY ALKYL AMINES, THEIR PRODUCTION AND MEDICAMENTS CONTAINING THEM.

摘要

PCT No. PCT/EP90/00380 Sec. 371 Date Sep. 3, 1991 Sec. 102(e) Date Sep. 3, 1991 PCT Filed Mar. 8, 1990 PCT Pub. No. WO90/10628 PCT Pub. Date Sep. 20, 1990.New aryloxy-alkylamine derivatives of the general formula I in which A signifies a benzene or thiophene ring, R and R1, independently of one another, each hydrogen, alkyl, halogen, CF3 or alkoxy, R2 alkyl, cycloalkyl, alkenyl, alkynyl, alkaryl or saturated or unsaturated aliphatic or aromatic acyl, R3 and R4 in each case hydrogen, alkyl, alkenyl, alkynyl or cycloalkyl with, in each case, up to 8 C-atoms, whereby R3 and R4 can be the same or different but are not simultaneously hydrogen or R3 and R4, together with the nitrogen atom connecting them, form a 5- to 7-membered saturated ring or a saturated heterocyclic ring which can possibly contain an oxygen or nitrogen atom as a further heteroatom in the ring, whereby an additional nitrogen atom can be substituted by an alkyl radical with up to 3 C-atoms, and their acid-addition salts possess interesting pharmaceutical properties and are especially suitable as anti-arrhythmics.