| 发明名称 |
Hepatic growth factor receptor is the MET proto-oncogene |
| 摘要 |
<p>The present invention relates to a complex comprising hepatocyte growth factor (HGF) and met proto-oncogene protein. The present invention also relates to methods for detecting the presence of HGF ligand, met proto-oncogene receptor and methods for isolating either the ligand or receptor or complex comprising both. The present invention further relates to methods of diagnostic proliferative disorders and diseases such as hepatitis or hepatocarcinogenesis by detecting these ligand-receptor pairs.</p> |
| 申请公布号 |
AU652031(B2) |
申请公布日期 |
1994.08.11 |
| 申请号 |
AU19920012738 |
申请日期 |
1992.01.15 |
| 申请人 |
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, |
发明人 |
DONALD P BOTTARO;JEFFREY S. RUBIN;DONNA FALETTO;ANDREW M CHAN;GEORGE F VANDE WOUDE;STUART A. AARONSON |
| 分类号 |
C07K17/00;A61K38/00;A61K38/18;A61K38/19;A61K38/48;A61K39/395;A61P35/00;C07K14/475;C07K14/52;C07K14/705;C07K14/71;C07K14/82;C07K16/00;C07K16/22;C07K16/24;C07K16/28;C07K16/32;C07K19/00;C12N5/06;C12N5/08;C12N15/09;C12P21/08;C12Q1/68;G01N33/53;G01N33/566;G01N33/574;G01N33/576;G01N33/68;(IPC1-7):G01N33/566;C07K15/06 |
主分类号 |
C07K17/00 |
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