| 发明名称 |
STABLY TRANSFECTED CELL LINES EXPRESSING GABA-A RECEPTORS |
| 摘要 |
The present invention relates to a stably co-transfected cell line capable of expressing a human GABAA receptor, which receptor comprises the .alpha.1.beta.3.gamma.2, .alpha.2.beta.3.gamma.2, .alpha.5.beta.3.gamma.2, .alpha.1.beta.1.gamma.2S, .alpha.1.beta.2.gamma.2, or .alpha.6.beta.3.gamma.2 subunit combin ation to membrane preparations derived from cultures thereof; and to the use of the cell line in designing and developing GABAA receptor subtype-selective medicaments.
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| 申请公布号 |
CA2151236(A1) |
申请公布日期 |
1994.06.23 |
| 申请号 |
CA19932151236 |
申请日期 |
1993.12.07 |
| 申请人 |
MERCK SHARP & DOHME LIMITED |
发明人 |
HADINGHAM, KAREN;WHITING, PAUL J. |
| 分类号 |
G01N33/566;A61K38/17;C07K14/705;C07K14/72;C12N5/10;C12N15/09;C12N15/12;C12P21/02;C12R1/91;G01N33/15;G01N33/50;G01N33/68;(IPC1-7):C12N5/10;C07K17/02;G01N33/567 |
主分类号 |
G01N33/566 |
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