摘要 |
PURPOSE:To provide a new and useful ACE-inhibiting oligopeptide, an ACE- inhibiting agent and a hypotensor. CONSTITUTION:The angiotensin converting enzyme inhibiting agent or the hypotensor contains one or more substances selected from L-Leu-L-Ser-L-Pro, L-Leu-L-Gln-L-Pro, L-Val-L-Ser-L-Pro, L-Leu-L-Leu-L-Pro, L-Leu-L-Asn-L-Pro, L-Phe-L-Leu-L-Pro, L-Leu-L-Ala-L-Ala, L-Val-L-Ala-L-Ala, L-Leu-L-Gln-L-Gln, L-Val-L-Ala-L-Tyr, L-Leu-L-Ala-L-Tyr, L-Leu-L-Ser-L-His, its acid addition salt, L-lle-L-Arg-L-Ala, its acid addition salt, L-Leu-L-Arg-L-Pro, its acid addition salt, L-Ile-L-Arg-L-Ala-L-Gln-L-Gln, its acid addition salt, L-Tyr-Val, L-Leu-L- Tyr, L-Leu-L-Phe, L-Phe-L-Tyr, L-Tyr-L-Arg and its pharmacologically permissible acid addition salt as an active component. |