发明名称 Diamine platinum(IV) complexes having mixed carboxylate ligands as antitumor agents
摘要 Platinum(IV) complexes with mixed carboxylato ligands having the formula: <IMAGE> where X1 and X2 are carboxylato, or are jointly dicarboxylato, where 1 Y and Y2 are carboxylato, and where Z is either diaminocyclohexane or ethylenediamine, have been found to have desirable antitumor activity, as well as relatively low levels of toxicity.
申请公布号 US5288887(A) 申请公布日期 1994.02.22
申请号 US19920978788 申请日期 1992.11.19
申请人 BOARD OF REGENTS, THE UNIVERSITY TEXAS SYSTEM 发明人 KHOKHAR, ABDUL R.;SIDDIK, ZAHID H.;AL-BAKER, SALAAM
分类号 C07F15/00;(IPC1-7):C07F15/00;A61K31/28 主分类号 C07F15/00
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