发明名称 |
Diamine platinum(IV) complexes having mixed carboxylate ligands as antitumor agents |
摘要 |
Platinum(IV) complexes with mixed carboxylato ligands having the formula: <IMAGE> where X1 and X2 are carboxylato, or are jointly dicarboxylato, where 1 Y and Y2 are carboxylato, and where Z is either diaminocyclohexane or ethylenediamine, have been found to have desirable antitumor activity, as well as relatively low levels of toxicity.
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申请公布号 |
US5288887(A) |
申请公布日期 |
1994.02.22 |
申请号 |
US19920978788 |
申请日期 |
1992.11.19 |
申请人 |
BOARD OF REGENTS, THE UNIVERSITY TEXAS SYSTEM |
发明人 |
KHOKHAR, ABDUL R.;SIDDIK, ZAHID H.;AL-BAKER, SALAAM |
分类号 |
C07F15/00;(IPC1-7):C07F15/00;A61K31/28 |
主分类号 |
C07F15/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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