发明名称 Method of producing 7-(substituted)-9-[(substituted glycyl)-amidol]-6-demethyl-6-deoxytetra-cyclines
摘要 The invention provides a novel method for producing compounds of the formula I: (* CHEMICAL STRUCTURE *) I wherein X and R are defined in the specifications. The invention also provides a method for making intermediates useful to produce the compounds of formula I. Utilizing a common intermediate, the novel method efficiently produces compounds of the formula I.
申请公布号 US5284963(A) 申请公布日期 1994.02.08
申请号 US19920928588 申请日期 1992.08.13
申请人 AMERICAN CYANAMID COMPANY 发明人 SUM, PHAIK-ENG;LEE, VING J.
分类号 A61K31/65;A61K31/165;A61P31/00;A61P31/04;C07C;C07C231/02;C07C231/12;C07C237/26;C07D203/08;C07D205/04;C07D207/06;C07D233/56;C07D249/04;C07D249/08;C07D295/14;C07D295/15;C07D521/00;(IPC1-7):C07C233/64;C07C235/32 主分类号 A61K31/65
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