发明名称 NOVEL ADENOSINE DERIVATIVES
摘要 Novel substituted adenosine derivatives of formula (I), or a pharmaceutically acceptable salt thereof, wherein X represents hydrogen, halogen, amino, perhalomethyl, acetamido, cyano, C1-6-alkyl, C1-6-alkoxy, C1-6-alkylthio or C1-6-alkylamino; R<1> is -NR<2>R<3>, -YR<4>, wherein Y is oxygen or sulphur; R<2> is C1-6-alkyl; R<3> is phenyl or C1-6-alkyl, which may be substituted with phenyl or phenoxy; R<4> is naphthyl; partly saturated naphthyl; C1-6-alkyl, which may be substituted with phenoxy or phenyl, which may be substituted with nitro, halogen or amino; or C3-8-cycloalkyl, which may be substituted with phenyl or phenoxy, which have been found useful for treating central nervous system ailments.
申请公布号 WO9323417(A1) 申请公布日期 1993.11.25
申请号 WO1993DK00157 申请日期 1993.05.12
申请人 NOVO NORDISK A/S 发明人 KNUTSEN, LARS, JACOB, STRAY;LAU, JESPER
分类号 A61K31/70;A61K31/7042;A61K31/7052;A61K31/7076;A61P9/00;A61P25/00;C07H19/16;C07H19/167;(IPC1-7):C07H19/16 主分类号 A61K31/70
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