发明名称 |
COMPOSITIONS AND METHODS FOR PACE 4 AND 4.1 GENE AND POLYPEPTIDES IN CELLS |
摘要 |
Compositions and methods are provided for endopeptidases and their production, and for enhanced efficiencies of processing heterologous precursor polypeptides to mature polypeptides. These compositions and methods utilize recombinant PACE 4 and 4.1, mammalian endopeptidases that are specific for dibasic amino acid sites. Therapeutic compositions and methods employing PACE 4 or 4.1 or their inhibitors are also provided. |
申请公布号 |
WO9318159(A3) |
申请公布日期 |
1993.11.11 |
申请号 |
WO1993US02147 |
申请日期 |
1993.03.09 |
申请人 |
CHIRON CORPORATION |
发明人 |
BARR, PHILIP, J.;KIEFER, MICHAEL, C. |
分类号 |
C12N15/09;A61K38/00;A61K38/55;C07H21/04;C12N1/21;C12N5/10;C12N9/64;C12N15/57;C12R1/00;C12R1/91 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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