发明名称 |
Method and apparatus for biopolymer synthesis |
摘要 |
Method and apparatus for synthesizing biopolymers, such as polypeptides and polynucleotides. The apparatus includes plural reaction vessels in which subunit coupling to biopolymers in a particle suspension is carried out. The vessels are connected to common valving structure for use in mixing the suspension and removing suspension liquid. In one embodiment, a robotic arm in the apparatus is operable to transfer reaction solution to the reaction vessels, and to transfer particle suspensions from the reaction vessels to a mixing vessel and back to the reaction vessels. The method can be used to produce preferably equi-molar amounts of different-sequence biopolymers, such as polypeptides and polynucleotides.
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申请公布号 |
US5252296(A) |
申请公布日期 |
1993.10.12 |
申请号 |
US19910652194 |
申请日期 |
1991.02.06 |
申请人 |
CHIRON CORPORATION |
发明人 |
ZUCKERMANN, RONALD N.;HEUBNER, VERENA D.;SANTI, DANIEL V.;SIANI, MICHAEL A. |
分类号 |
B01J19/00;C07H21/00;C07K1/04;C07K7/08;C07K14/575;C07K16/00;C40B40/06;C40B40/10;C40B60/14;(IPC1-7):G05D7/00 |
主分类号 |
B01J19/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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