Compositions containing indole-2-carboxylate compounds for treatment of CNS disorders

摘要

Compositions containing certain indole-2-carboxylate compounds and derivatives are described as being therapeutically effective in treatment of CNS disorders resulting from neurotoxic damage or neurodegenerative diseases, particularly those CNS disorders resulting from ischemic events. Preferred compounds are of the formula <IMAGE> wherein each of R5 and R6 is independently selected from hydrido, bromo, chloro and fluoro, and wherein each of R10 and R12 is independently selected from hydrido and lower alkyl, and pharmaceutically-acceptable salts thereof.