发明名称 |
ARYLALKANOIC ACID RESOLUTION |
摘要 |
In a process for preparing predominantly one enantiomer of an optically-active 2-arylalkanoic acid by biotransformation, using an appropriate enzyme, of a mixture of enantiomers of an ester of the acid, the ester is derived from an alcohol of more than 4 carbon atoms, and the enzyme is in crude or only partially purified form. For example, S-ketoprofen can be thus prepared economically and in high ee, from racemic octyl ketoprofen. |
申请公布号 |
WO9304190(A1) |
申请公布日期 |
1993.03.04 |
申请号 |
WO1992EP01896 |
申请日期 |
1992.08.19 |
申请人 |
LABORATORIOS MENARINI S.A. |
发明人 |
EVANS, CHRISTOPHER, THOMAS;MCCAGUE, RAYMOND;TAYLOR, STEPHEN, JOHN, CLIFFORD;CARGANICO, GERMANO |
分类号 |
C12P7/40;C12P41/00;C12R1/72;(IPC1-7):12P41/00;12P7/40 |
主分类号 |
C12P7/40 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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