摘要 |
This invention relates to new 2-pyrazoline derivatives represented by the following general formula (A): (A) ( wherein R1 denotes a pyridyl, a pyrazyl or an alkoxyl group; and R2 stands for hydrogen atom, an alkyl, a pyridyl, a furyl, phenyl or a substituted phenyl group ), and to a process for producing the same. This invention also relates to agents for treating cerebrovascular diseases containing, as active ingredients, a 2-pyrazoline derivative represented by the following general formula (G): (G) ( wherein R3 denotes hydrogen atom, an alkyl, acetyl, an alkoxycarbonyl, an amino, benzoyl, a substituted benzoyl, a pyridylcarbonyl, a furylcabonyl, a thienylcarbonyl, a pyrazylcarbonyl, an N-substituted carbamoyl, an N-sub-stituted thiocarbamoyl, or carboxyl group; and R4 stands for hydrogen atom, an alkyl, a pyridyl, a thienyl, a furyl, cyclohexyl, phenyl or a substituted phenyl group ) or a pharmaceutically acceptable salt thereof. |
申请人 |
MITSUI TOATSU CHEMICALS, INC. |
发明人 |
YAMASHITA, HIROYUKI;ODATE, MAKOTO;IIZUKA, HAJIME;KAWAZURA, HIROSHI;SHIGA, YOSHIO;NAMEKAWA, HIROSHI |