发明名称 New 2-piperazinylbenzimidazole derivatives.
摘要 <p>A description of new 2-piperazinylbenzimidazole derivatives, of general formula &lt;CHEM&gt; where R can be a hydrogen atom, a short chain alkyl group and a phenyl radical, substituted in position four by a halogen, and R1 can be a hydrogen atom, an alkoxycarbonyl radical, a hydroxymetyl group and a diphenylmethyl group, and their addition salts with pharmaceutically acceptable acids. these compounds are pharmacologically active as antagonists of serotonin 5HT3 receptors.</p>
申请公布号 EP0512939(A1) 申请公布日期 1992.11.11
申请号 EP19920500056 申请日期 1992.05.08
申请人 FABRICA ESPANOLA DE PRODUCTOS QUIMICOS Y FARMACEUTICOS, S.A. (FAES) 发明人 ORJALES-VENERO, AURELIO;GARCIA-DOMINGUEZ, NEFTALI;RUBIO-ROYO, VICTOR;RODES-SOLANES, ROSA
分类号 A61K31/495;A61K31/496;A61P1/08;A61P25/04;A61P25/06;A61P25/20;A61P43/00;C07D235/30 主分类号 A61K31/495
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