发明名称 |
New 2-piperazinylbenzimidazole derivatives. |
摘要 |
<p>A description of new 2-piperazinylbenzimidazole derivatives, of general formula <CHEM> where R can be a hydrogen atom, a short chain alkyl group and a phenyl radical, substituted in position four by a halogen, and R1 can be a hydrogen atom, an alkoxycarbonyl radical, a hydroxymetyl group and a diphenylmethyl group, and their addition salts with pharmaceutically acceptable acids. these compounds are pharmacologically active as antagonists of serotonin 5HT3 receptors.</p> |
申请公布号 |
EP0512939(A1) |
申请公布日期 |
1992.11.11 |
申请号 |
EP19920500056 |
申请日期 |
1992.05.08 |
申请人 |
FABRICA ESPANOLA DE PRODUCTOS QUIMICOS Y FARMACEUTICOS, S.A. (FAES) |
发明人 |
ORJALES-VENERO, AURELIO;GARCIA-DOMINGUEZ, NEFTALI;RUBIO-ROYO, VICTOR;RODES-SOLANES, ROSA |
分类号 |
A61K31/495;A61K31/496;A61P1/08;A61P25/04;A61P25/06;A61P25/20;A61P43/00;C07D235/30 |
主分类号 |
A61K31/495 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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