ASSAY AND KIT FOR THE DETECTION OF CHROMOSOMAL ABNORMALITIES

摘要

2109518 9219775 PCTABS00017 A target sequence including a chromosomal translocation or other abnormality is detected by reacting the target sequence, under hybridising conditions in a homogeneous phase, with excess amounts of capture and reporter oligonucleotide probes which are respectively complementary to different regions of the target sequence; and separating and detecting any resultant hybrid that has both labels.