CNS CELL DIFFERENTIATION FACTOR, ITS PREPARATION AND USE

摘要

The invention provides a new differentiation-promoting factor of molecular weight 20-25 kilodaltons when isolated by SDS-PAGE. The factor causes O-2A progenitor cells to differentiate expressing GFAP. The new factor is a secreted protein. The invention provides therapeutic formulations comprising the new factor, and the use of the factor and those formulations in treating conditions which involve a factor-sensitive or factor-responsive cell type.