NAPHTHYLALKYLAMINO-SUBSTITUTED SULFAMOYLBENZOIC ACID DERIVATIVES, AND THE USE THEREOF AS MEDICINES

摘要

Naphthylalkylamino-substituted sulfamoylbenzoic acid derivatives, processes for the preparation thereof and the use thereof as medicines. Compounds I <IMAGE> I R(1) hydrogen, (C1-C4)-alkyl and Na, K, NH4, Ca, Mg, R(2) and R(3) hydrogen, alkyl groups which can also be linked together in a ring, X oxygen, sulfur, SO, SO2, NR(6) [with R(6)=hydrogen-alkyl], CH2, CO, or a bond, R(4) phenyl, thienyl, which are unsubstituted or substituted R(5) hydrogen, (C1-C4)-alkyl, n 1, 2, 3 or 4, where the naphthyl system is unsubstituted or substituted like the phenyl radical of R(4), and where X and R(4) together can also be Cl are medicaments for treating sickle-cell anemia.