发明名称 |
PLATELET BINDING INHIBITORS |
摘要 |
Case Docket No. APC 85-78 Express Mail Label No. B 77611926 Peptides of the general formula H2N-(Ch)-Arg-Gly-Asp-(Cx)-H and the derivatives thereof described herein, wherein (Cx) and (Ch) each contains 1 to 20 amino acid residues and (Ch) contains at least one Lys or Arg residue, or at least one of each, inhibit platelet-fibrinogen binding and platelet-platelet aggregation and are thus useful inhibitors of cell adhesion. |
申请公布号 |
CA1306581(C) |
申请公布日期 |
1992.08.18 |
申请号 |
CA19860521502 |
申请日期 |
1986.10.27 |
申请人 |
SCRIPPS CLINIC AND RESEARCH FOUNDATION |
发明人 |
ZIMMERMAN, THEODORE S.;RUGGERI, ZAVERIO M.;HOUGHTEN, RICHARD |
分类号 |
C07K5/10;A61K38/00;A61P7/02;C07K7/06;C07K7/08;C07K14/00;C07K14/745;C07K14/75 |
主分类号 |
C07K5/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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