发明名称 |
3,9-DIAZABICYCLO (3.3.1) NONAN-7-YL DERIVATIVES, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
摘要 |
Compounds of formula (I) wherein X is a phenyl group or a monocyclic 5 or 6 membered heteroaryl group, either of which group is optionally fused to a saturated or unsaturated 5-7 membered carbocyclic or heterocyclic ring; A is linking moiety; Z is C1-6 alkyl, C3-8 cycloalkyl, C3-8 cycloalkyl C1-4 alkyl, phenyl, naphthyl, phenyl C1-4 alkyl or naphthyl C1-4 alkyl wherein a phenyl or naphthyl moiety is optionally substituted by one or more of halo, C1-6 alkoxy or C1-6 alkyl; R is hydrogen or methyl having 5-HT3 receptor antagonist activity. |
申请公布号 |
WO9205174(A1) |
申请公布日期 |
1992.04.02 |
申请号 |
WO1991GB01629 |
申请日期 |
1991.09.23 |
申请人 |
BEECHAM GROUP PLC |
发明人 |
KING, FRANCIS, DAVID;GREGORY, JULIAN, ANTHONY |
分类号 |
A61K31/495;A61P1/08;A61P25/00;A61P25/04;A61P43/00;C07D471/08;C07D519/00 |
主分类号 |
A61K31/495 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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