PROCESS FOR THE PREPARATION OF 9-BETA-D-ARABINOFURANOSYL-2-FLUOROADENINE 5'-PHOSPHATE
摘要
A process for the preparation of 9-beta-D-arabinofuranosyl-2-fluoroadenine 5'-phosphate (II) from 9-beta-D-arabinofuranosyl-2-fluoroadenine (I) by phosphorylation is described. The reaction is conducted under anhydrous conditions, particularly where (I) is dried extensively in a vaccum. The compound (II) is an antileukemia and antiviral drug.
申请公布号
WO9200312(A1)
申请公布日期
1992.01.09
申请号
WO1991US04566
申请日期
1991.06.26
申请人
ASH STEVENS, INC.
发明人
BLUMBERGS, PETER;KHAN, MOHAMMED, S.;KALAMAS, RICHARD, L.;PATEL, AMBALAL;LAMONTAGNE, MAURICE, P.
