发明名称 |
ETHER LIPID-NUCLEOSIDE COVALENT CONJUGATES |
摘要 |
Ether lipid nucleoside covalent conjugates and derivatives thereof are disclosed, along with pharmaceutical compositions containing the same and methods of using the same to combat HIV-1 infections. Illustrative are 3'-Azido-3'-deoxythymidine-5'-monophosphate-D,L-3 octadecanamido-2-ethoxypropane and 3'-Azido-3'-deoxythymidine-5' butyrate- gamma -N,N,N-trimethyl-ammonium- beta -(1-phospho-2-ethoxy-3-hexadecyloxypropane). |
申请公布号 |
WO9119726(A1) |
申请公布日期 |
1991.12.26 |
申请号 |
WO1991US04289 |
申请日期 |
1991.06.14 |
申请人 |
WAKE FOREST UNIVERSITY;THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL |
发明人 |
PIANTADOSI, CLAUDE;MARASCO, CANIO, J., JR.;KUCERA, LOUIS, S. |
分类号 |
A61K31/715;A61P31/12;C07F9/09;C07F9/10;C07H19/10;C07H19/20;C07H19/207 |
主分类号 |
A61K31/715 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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