| 摘要 |
The invention concerns compounds of formula <IMAGE> (I) or salts thereof; wherein: alpha and beta together represent a bond and additionally when B is an electron withdrawing group alpha can also represent OH and beta can represent hydrogen; Ar is an optionally substituted aryl or heteroaryl radical; R represents hydrogen or an optionally substituted alkyl or aralkyl group; R1 and R2 are the same or different and are selected from hydrogen and saturated or unsaturated, cyclic or acyclic aliphatic hydrocarbon residues optionally substituted by one or more groups selected from halogen, OH, carboxy, CN, alkoxy, alkylthio, aryloxy, alkoxycarbonyl, amino, substituted amino, and optioanlly substituted aryl or heteroaryl; A represents a group of formula -XR3 wherein X is a group of formula -(CHR6)p-Y-(CHR7)q- in which formula: Y represents -O+13, -S-, NR8 or a direct bond, p and q each represent 0, 1 or 2 R6, R7 and R8 independently represent hydrogen or lower alkyl and R3 is an optionally substituted nitrogen ring heteroaryl radical optionally containing other ring heteratoms selected from oxygen, nitrogen or sulphur; B represents haloalkyl, optionally substituted phenyl, -CN, -CHO, -CH(Oloweralkyl)2 or -CH2OH.
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