发明名称 PROCESS FOR THE PRODUCTION OF GLYCOSAMINO-GLUCANE SALTS AND MEDICAL PREPARATIONS CONTAINING THEM
摘要 PCT No. PCT/EP89/00605 Sec. 371 Date Nov. 15, 1990 Sec. 102(e) Date Nov. 15, 1990 PCT Filed May 30, 1989 PCT Pub. No. WO90/12589 PCT Pub. Date Nov. 1, 1990.Salts of glycosaminoglycans (heparin, its fractions or fragments which are supersulfated, dermatan sulfate, heparan sulfate, and modified heparins) with bases of formula (I), <IMAGE> (I) wherein R1, R2, R3, and R4 represent H, alkyl, or cycloalkyl; R5 and R6 represent H, or alkyl; R7 and R8 represent H or alkyl; n and m are integers from 1-4 and X is -O-CO-O-, which salts have the pharmacological properties of the glycosaminoglycans themselves, and are orally and rectally administrable.
申请公布号 HU893408(D0) 申请公布日期 1991.10.28
申请号 HU19890003408 申请日期 1989.05.30
申请人 ITALFARMACO S.P.A.,IT 发明人 DAL POZZO,ALMA,IT;ACQUASALIENTE,MAURIZIO,IT;SPORTOLETTI,GIANCARLO,IT;SARRET,MONIQUE,IT;FERRUTI,PAOLO,IT;DE SANTIS,FRANCESCO,IT
分类号 C07C233/36;A61K;A61K31/715;A61P3/06;A61P7/02;C07C;C07C211/63;C07C219/02;C07C229/06;C07C237/00;C07C237/04;C07C237/10;C07C271/06;C07C271/20;C07C275/04;C07C275/14;C08B;C08B37/00;C08B37/10 主分类号 C07C233/36
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