Pharmaceuticals, phosphorus-containing 2-isoxazolines and isoxazoles contained therein

摘要

Pharmaceuticals containing or composed of at least one compound of the formula I and/or one of its physiologically tolerated salts where appropriate, where the compounds of the formula I can, where appropriate, be in the form of pure stereoisomers or mixtures thereof; formula I is: <IMAGE> (I) in which R1=organic radical or halogen, A=C,C single or C,C double bond, n=0, 1 or 2, and X and Y = alkyl radical or = OR2 or NR2R3 with R2 and R3=H or optionally substituted aliphatic radical. The pharmaceuticals are suitable for the prophylaxis and/or treatment of diseases of the immune system, especially of tumors, infections and/or autoimmune diseases of the human or animal body and for use as adjuvants for vaccines. Some of the compounds of the formula I are new; the compounds can be prepared by special processes.