Condensed diazepinones, processes for preparing them and pharmaceutical compositions containing these compounds
摘要
Novel condensed diazepinones of general formula I <IMAGE> (I) wherein B represents one of the divalent groups <IMAGE> +TR <IMAGE> and X, A1, A2 and R1-R10 are as defined herein. The condensed diazepinones are suitable as vagal pacemakers for the treatment of bradycardia and bradyarrhythmia and they have spasmolytic effects on peripheral organs, particularly the colon, bladder and bronchi.
申请公布号
US5002943(A)
申请公布日期
1991.03.26
申请号
US19890366828
申请日期
1989.06.15
申请人
MIHM, GERHARD;EBERLEIN, WOLFGANG;ENGEL, WOLFHARD;TRUMMLITZ, GUNTER;MAYER, NORBERT;DE JONGE, ADRIAN;DOODS, HENRI
发明人
MIHM, GERHARD;EBERLEIN, WOLFGANG;ENGEL, WOLFHARD;TRUMMLITZ, GUNTER;MAYER, NORBERT;DE JONGE, ADRIAN;DOODS, HENRI