| 发明名称 |
PRODUCTION AND PURIFICATION OF RECOMBINANT HUMAN INTERLEUKIN-3 AND MUTEINS THEREOF |
| 摘要 |
Recombinantly produced IL-3 is purified in a series of steps, initially employing hydrophobic interaction, followed by ion-exchange chromatography and gel filtration. Furthermore methods are provided for improved production of recombinant hIL-3 either in glycosylated form from mammalian and yeast cells or in unglycosylated form from prokaryotes. |
| 申请公布号 |
WO9010705(A3) |
申请公布日期 |
1990.11.01 |
| 申请号 |
WO1990NL00030 |
申请日期 |
1990.03.15 |
| 申请人 |
GIST-BROCADES N.V. |
发明人 |
PERSOON, NICOLAAS, LUDOVICUS, MARIA;VAN LEEN, ROBERT, WILLEM |
| 分类号 |
C12N15/09;A61K38/00;A61P7/00;A61P37/00;A61P43/00;C07K1/20;C07K14/52;C07K14/54;C12N15/27;C12N15/75;C12N15/86;C12P21/00;C12R1/01;C12R1/10;C12R1/19;C12R1/91 |
主分类号 |
C12N15/09 |
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