发明名称 CYCLIC AMINE COMPOUNDS AND THEIR USE
摘要 A cyclic amine compound of the formula <CHEM> wherein B means a saturated or unsaturated 5- to 7-membered aza-heterocyclic group which may be substituted; A means a bond or an alkylene or alkenylene group which may be substituted by hydrocarbon residues, oxo, hydroxyimino, and/or hydroxy, ___ means either a single bond or a double bond (provided that when A means a bond, ___ means a single bond); R2 and R3 independently mean a hydrogen atom or a hydrocarbon residue which may be substituted (provided that both of R2 and R3 are not hydrogen atoms) or jointly form a cyclic amino group together with the adjacent nitrogen atom, n is 0, 1 or 2 and p is 1 or 2 or a physiologically acceptable salt thereof. The compounds are useful for therapy of cerebral edema, acute symptoms in cerebral apoplexy and protection of brain and nerve cell, or useful as anticholinesterase or as brain function-improving agent.
申请公布号 AU4791190(A) 申请公布日期 1990.08.09
申请号 AU19900047911 申请日期 1990.01.11
申请人 TAKEDA CHEMICAL INDUSTRIES, LTD. 发明人 GIICHI GOTO;HIDEFUMI YUKIMASA;TETSUJI IMAMOTO
分类号 C12N9/99;A61K31/00;A61K31/44;A61K31/4409;A61K31/4418;A61K31/445;A61K31/4465;A61K31/451;A61P9/00;A61P25/28;C07D211/26;C07D211/32;C07D211/70;C07D213/36;C07D213/38;C07D213/50;C07D521/00 主分类号 C12N9/99
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