摘要 |
<p>A process for the preparation of 2,2'-bipyridyls by reacting a pyridine base in the presence of a nickel catalyst which comprises a significant amount of elemental nickel bound on a suitable support. The coupling reaction takes place in several reactor designs at a temperature of about 200-240°C and a pressure sufficient to maintain at least some of the base in a liquid state during the reaction.</p> |