摘要 |
Compounds of structure (I) <CHEM> in which R<1> is hydrogen, C1-6alkyl, C1-6alkoxy, C1-6alkoxylC1-6alkyl, C3-6cycloalkyl, C3-6cycloalkylC1-6alkyl, phenyl or phenylC1-6alkyl, the phenyl groups being optionally substituted; R<2> is hydrogen, C1-6alkyl, C1-6alkoxy, CO2H or CO2C1-6alkyl; m is 1, 2 or 3; p is 0 to 4; R<3> is hydrogen, C1-6alkyl, phenyl, C1-6alkoxy, C1-6alkylthio, C1-6alkanoyl, amino, C1-6alkylamino, di-C1-6alkylamino, halogen, trifluoromethyl or cyano; n is 1 or 2; and X is S, O, NH or NC1-4alkyl; processes for their preparation, intermediates used in their preparation, pharmaceutical compositions containing them and their use in therapy as anti-ulcer agents. |