MACROLIDE COMPOUNDS

摘要

Fermentation product A83543 (1), comprising major components A83543A and A83543D and minor components A83543B, A83543C, A83543E, A983543F, A83543G, A83543H and A83543J, is produced by a newly described species, Saccharopolyspora spinosa. The A83543 components and their acid-addition salts (A83543 compounds) are useful as insecticides, particularly against Lepidoptera and Diptera species. Insecticidal, miticidal or ectoparasiticidal combinations, compositions and methods are provided. wherein R is H or a group selected from R<2> is R<1>, R<3>, R<5> and R<6> are hydrogen or methyl; R4 is methyl or ethyl; or an acid addition salt thereof the compounds when R is other than hydrogen.